Reference
Biohacking
Glossary
Quick-reference definitions for the compounds, peptides, and supplements used in performance and longevity protocols.
BPC-157
Body Protection Compound 157 · Peptide
BPC-157 is a synthetic peptide derived from a stomach protein. It accelerates healing of tendons, ligaments, muscles, and gut lining. Extensively studied in animal models with robust anecdotal human evidence.
GHK-Cu
Copper Peptide GHK-Cu · Peptide
GHK-Cu stimulates collagen synthesis, wound healing, and stem cell activation. Has strong anti-inflammatory properties and has been shown to reverse aging-associated gene expression patterns.
Ipamorelin
Ipamorelin Acetate · Peptide
Ipamorelin is a selective GH secretagogue that triggers natural growth hormone pulses. Unlike other GH peptides, it doesn't elevate cortisol or prolactin. Improves sleep, recovery, and body composition.
Melanotan I
Afamelanotide · Peptide
Melanotan I (afamelanotide) is a non-selective melanocortin receptor agonist. FDA-approved as Scenesse for erythropoietic protoporphyria. Provides deep tanning without UV exposure. Longer half-life and cleaner profile than MT-II.
Melanotan II
Melanotan II (MT-II) · Peptide
MT-II activates melanocortin 1/3/4/5 receptors producing stronger tanning than MT-I, significant appetite suppression via MC4R, libido enhancement, and some thermogenic fat loss. More potent but shorter acting than Melanotan I.
NMN
Nicotinamide Mononucleotide · Longevity
NMN is a direct precursor to NAD+, the molecule central to energy metabolism and DNA repair. NAD+ declines with age — supplementation supports cellular energy, mitochondrial function, and longevity pathways.
Retatrutide
Retatrutide (RETA) · Metabolic Peptide
Retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors — a triple mechanism that produced up to 24% body weight reduction in Phase 2 trials, exceeding semaglutide. Phase 3 trials ongoing.
Semax
Synthetic ACTH/MSH Fragment · Nootropic Peptide
Semax is a synthetic peptide based on ACTH that dramatically increases BDNF (Brain-Derived Neurotrophic Factor). Enhances memory, focus, and processing speed. Neuroprotective. Prescription drug in Russia and Ukraine.
TB-500
Thymosin Beta-4 · Peptide
TB-500 promotes whole-body healing by upregulating actin, the protein that builds cell structure. Reduces inflammation, scar tissue, and improves range of motion. Synergistic with BPC-157.
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